SAB4300263

Anti-phospho-CFL1/CFL2 (pTyr⁸⁸) antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Anti-CFL antibody produced in rabbit, Anti-NEM7 antibody produced in rabbit, Anti-cofilin 1 (non-muscle) / cofilin 2 (muscle) antibody produced in rabbit
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: ~19 kDa
• Espèces réactives: human, mouse, rat
• Concentration: 1 mg/mL
• Technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• Isotype: IgG
• Séquence immunogène: (A-T-YP-E-T)
• Numéro d'accès NCBI: NP_005498.1; NP_068733.1
• Numéro d'accès UniProt: P23528
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pTyr88)
• Informations sur le gène: human ... CFL1(1072) , CFL2(1073)

Description

Immunogène

Peptide sequence around phosphorylation site of tyrosine 88 (A-T-Y(p)-E-T), according to the protein CFL1/CFL2.

Caractéristiques et avantages

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Description de la cible

Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

Forme physique

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable