P5669

Pyridoxine

≥98%

• Synonyme(s) : Pyridoxol, Vitamin B₆
• Formule empirique (notation de Hill): C₈H₁₁NO₃
• Numéro CAS: 65-23-6
• Poids moléculaire : 169.18
• Numéro CE : 200-603-0
• Numéro MDL: MFCD00006335
• Code UNSPSC : 12352104
• ID de substance PubChem : 24898690
• Nomenclature NACRES : NA.28

Propriétés

• Pureté: ≥98%
• Forme: powder
• Technique(s): HPLC: suitable
• Couleur: white to off-white
• Pf: 159-162 °C (lit.)
• Chaîne SMILES: Cc1ncc(CO)c(CO)c1O
• InChI: 1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3
• Clé InChI: LXNHXLLTXMVWPM-UHFFFAOYSA-N
• Informations sur le gène: human ... CYP1A2(1544)

Description

Description générale

Pyridoxine (vitamin B6) is a form of vitamin B6. Other forms include the aldehyde pyridoxal and the amide pyridoxamine. It is an important cofactor for metabolism.

Vitamin B group are water-soluble and exists in six forms which includes the pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phospate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. Vitamin B₆ is distributed in nuts, whole grains and animal meat.

Application

Pyridoxine has been used as a component of:

• artificial diet for sugarcane aphid pest
• modified Strullu and Romand (MSR) medium for carrot root organ culture
• Luria broth for E coli cultures

Pyridoxine is used in cell culture and other applications as a precursor to pyridoxal phosphate. It has been used as a standard in RP-HPLC (reversed phase high performance liquid chromatography) method. Pyridoxine has been used as a diet supplement to study lipid profile in rats.

Actions biochimiques/physiologiques

Pyridoxine plays a key role in cell maintenance and amino acid metabolism. Deficiency of vitamin B₆ leads to anemia especially in pregnant women and seizures in newborns. It serves as cofactor for heme biosynthesis during δ-amino levulinic acid formation, γ-aminobutyric acid (GABA) transaminase and glutamic acid decarboxylase. Vitamin B₆ also helps in reactive oxygen species (ROS) scavenging and helps plants in overcoming the abiotic and biotic stress.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves