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324R-1

Sigma-Aldrich

PSA (EP109) Rabbit Monoclonal Primary Antibody

Synonyme(s) :

APS, KLK2A1, P-30 antigen, gamma-seminoprotein, hK3, kallikrein-3, kallikrein-related peptidase 3, prostate specific antigen, semenogelase, seminin

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About This Item

Code UNSPSC :
12352203

Source biologique

rabbit

Niveau de qualité

100
500

Conjugué

unconjugated

Forme d'anticorps

Ig fraction of antiserum

Type de produit anticorps

primary antibodies

Clone

EP109, monoclonal

Description

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forme

buffered aqueous solution

Espèces réactives

human

Conditionnement

vial of 0.1 mL concentrate (324R-14)
vial of 0.5 mL concentrate (324R-15)
vial of 1.0 mL concentrate (324R-16)
vial of 1.0 mL pre-dilute ready-to-use (324R-17)
vial of 7.0 mL pre-dilute ready-to-use (324R-18)

Fabricant/nom de marque

Cell Marque

Concentration

0.1-0.5 μg/mL (predilute)
10-500 μg/mL (concentrate)

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)

Isotype

IgG

Contrôle

prostate carcinoma

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Visualisation

cytoplasmic

Informations sur le gène

human ... KLK3(354)

Description générale

Prostate-Specific Antigen (PSA) is a 33 kDa protein primarily produced by the prostatic epithelium and the epithelial lining of the periurethral glands. PSA is strongly expressed in both normal and neoplastic prostatic tissue. Anti-PSA is most useful in determining the prostatic origin of carcinomas in non-prostate tissues (metastatic disease) using IHC techniques.,,,

Qualité

Canada - IVD
European Union - IVD
Japan - RUO
United States - IVD

Attention

Do not freeze

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Notes préparatoires

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Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Prostate specific antigen: a decade of discovery -- what we have learned and where we are going.
Polascik, T.J., et al.
The Journal of Urology, 162, 293-306 (1999)
Immunohistochemical labelling for prostate specific antigen in nonprostatic tissues.
Alanen, K.A., et al.
Pathology Research and Practice, 192, 233-237 (1996)
Prostate-specific antigen.
Stenman, U.H., et al.
Seminars in Cancer Biology, 9, 83-93 (1999)
M Varma et al.
Histopathology, 47(1), 1-16 (2005-06-29)
Varma M & Jasani B (2005) Histopathology47, 1-16 Diagnostic utility of immunohistochemistry in morphologically difficult prostate cancer: review of current literatureImmunohistochemistry is widely used to distinguish prostate cancer from benign mimics and to establish the prostatic origin of poorly differentiated
U H Stenman et al.
Seminars in cancer biology, 9(2), 83-93 (1999-04-15)
Prostate specific antigen (PSA) is serine protease produced at high concentrations by normal and malignant prostatic epithelium. It is mainly secreted into seminal fluid, where it digests the gel forming after ejaculation. Only minor amounts of PSA leak out into

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