5.08773

PPACK, 2HCl

InSolution, ≥88%

• Synonyme(s) : InSolution PPACK, 2HCl, D-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone, 2HCl, H-D-Phe-Pro-Arg-chloromethylketone, 2HCl, PPACK, dihydrochloride InSolution
• Formule empirique (notation de Hill): C₂₁H₃₁ClN₆O₃ · 2HCl
• Poids moléculaire : 523.88
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥88% (HPLC)
• Forme: liquid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; avoid repeated freeze/thaw cycles; protect from light
• Température de stockage: −70°C

Description

Description générale

D-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone (PPACK) is a potent and specific inhibitor of thrombin with ideal, unbiased properties for use as an anticoagulant in blood gas, electrolyte, and iCa analyses.

Actions biochimiques/physiologiques

Reversible: no

Conditionnement

Packaged under inert gas

Avertissement

Toxicity: Standard Handling (A)

Forme physique

A 25 mM (5 mg/357 µl) sterile-filtered solution of PPACK, 2HCl (Cat. No. 520222) in H₂O.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.

Autres remarques

Rosado, J. A., et al. 2002. J. Biol. Chem.277, 42157.
Odake S., et al. 1995. J. Enzyme Inhib.9, 17.
Arni, R.K., et al. 1993. Biochemistry32, 4727.
Yamashita, T., et al. 1993. Thromb. Res.69, 93.
Schmaier, A.H., et al. 1992. Thromb. Res.67, 479.
Collen, D., et al. 1982. J. Lab. Clin. Med.99, 76.

Kettner, C., and Shaw, E. 1981. Methods Enzymol.80, 826.
Kettner, C., and Shaw, E. 1979. Thromb. Res.14, 969.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany