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492620

Sigma-Aldrich

Formaldehyde-d2 solution

~20 wt. % in D2O, 98 atom % D

Synonyme(s) :

Deuterated formaldehyde, Formalin-d2

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About This Item

Formule linéaire :
DCDO
Numéro CAS:
1664-98-8
Poids moléculaire :
32.04
Numéro MDL:
MFCD00144373
Code UNSPSC :
12352501
ID de substance PubChem :
24872765
Nomenclature NACRES :
NA.12

Pureté isotopique

98 atom % D

Concentration

~20 wt. % in D2O

Technique(s)

protein expression: suitable

Changement de masse

M+2

Chaîne SMILES 

[2H]C([2H])=O

InChI

1S/CH2O/c1-2/h1H2/i1D2

Clé InChI

WSFSSNUMVMOOMR-DICFDUPASA-N

Description générale

Formaldehyde-d2, isotopically labeled solution of formaldehyde.

Application

Formaldehyde-d2 solution is used in the synthesis of dimethylated peptides. It is also used in quantification of antigens in vaccine products.
Stable Isotope methyl labeling has led to quantification of antigens in influenza vaccine. It is also used in global antigen quantification of different types of protein-based vaccine and manufacturing intermediates.

Conditionnement

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Pictogrammes

Skull and crossbonesHealth hazard
GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Jue-Liang Hsu et al.
Analytical chemistry, 75(24), 6843-6852 (2003-12-13)
In this paper, we report a novel, stable-isotope labeling strategy for quantitative proteomics that uses a simple reagent, formaldehyde, to globally label the N-terminus and epsilon-amino group of Lys through reductive amination. This labeling strategy produces peaks differing by 28
Kevin Colizza et al.
Journal of the American Society for Mass Spectrometry, 29(4), 675-684 (2018-01-27)
Our efforts to lower the detection limits of hexamethylene triperoxide diamine (HMTD) have uncovered previously unreported gas-phase reactions of primary and secondary amines with one of the six methylene carbons. The reaction occurs primarily in the atmospheric pressure chemical ionization
Sheng-Yu Huang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1104, 40-48 (2018-11-15)
Determining the precursor/product ion pair and optimal collision energy are the critical steps for developing a multiple reaction monitoring (MRM) assay using triple quadruple mass spectrometer for protein quantitation. In this study, a platform consisting of stable isotope dimethyl labeling
Michelle D Gonsalves et al.
Xenobiotica; the fate of foreign compounds in biological systems, 51(4), 394-403 (2021-01-14)
Triacetone triperoxide (TATP) and hexamethylene triperoxide diamine (HMTD) are prominent explosive threats. Mitigation of peroxide explosives is a priority among the law enforcement community, with canine (K9) units being trained to recognise the scent of peroxide explosives. Herein, the metabolism
Chunli Wang et al.
Scientific reports, 6, 22645-22645 (2016-03-05)
Proteolysis is a major form of post translational modification which occurs when a protease cleaves peptide bonds in a target protein to modify its activity. Tracking protease substrates is indispensable for understanding its cellular functions. However, it is difficult to
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