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Merck

SRC

v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

Synonymes:
ASV, SRC1, c-SRC, p60-Src
Espèce(s):
Human SRC (6714), Mouse Src (20779), Rat Src (83805), Zebrafish src (325084), chicken SRC (396442), domestic cat SRC (101100378), dog SRC (485864), sheep SRC (101103084), cow SRC (535742), domestic guinea pig Src (100728509)
ID UniProtKB:
P12931, E1P5V4, Q76P87, Q86VB9, Q9H5A8
ID du gène:
  • Human(6714) Summary: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(20779) Rous sarcoma oncogene
  • Rat(83805) v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
  • Zebrafish(325084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • chicken(396442) v-src sarcoma viral oncogene
  • domestic cat(101100378) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • dog(485864) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • sheep(101103084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • cow(535742) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • domestic guinea pig(100728509) Rous sarcoma oncogene
  • naked mole-rat(101703827) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

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Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
695017
Acide phosphorique, ACS reagent, ≥85 wt. % in H2O,
Espèce(s)
human
345245
Acide phosphorique, 85 wt. % in H2O, 99.99% trace metals basis,
Espèce(s)
human
438081
Acide phosphorique, ACS reagent, ≥85 wt. % in H2O,
Espèce(s)
human
27109
Acide citrique, meets analytical specification of Ph. Eur., BP, USP, E330, anhydrous, 99.5-100.5% (based on anhydrous substance),
Espèce(s)
human
466123
Acide phosphorique, crystalline, ≥99.999% trace metals basis,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
05-677
Anticorps anti-phospho-Src (Tyr416), clone 9A6, clone 9A6, Upstate®, from mouse,
Espèces réactives
human, mouse
Application
immunoprecipitation (IP)
western blot
07-909
Anti-phospho-Src (Tyr418) Antibody, Upstate®, from rabbit,
Espèces réactives
chicken, human, mouse
Application
immunocytochemistry
immunohistochemistry
western blot
HPA030875
Anti-SRC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
western blot
04-772
Anti-Src Antibody, CT, clone NL19 | 04-772, clone NL19, Upstate®, from rabbit,
Espèces réactives
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
SAB5300367
Monoclonal Anti-SRC antibody produced in mouse, clone 1F11, ascites fluid,
Espèces réactives
human
Application
ELISA
flow cytometry
immunohistochemistry
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
S9692
SU 6656, ≥98% (HPLC),
Espèce(s)
human
R2146
Radicicol from Diheterospora chlamydosporia, solid,
Espèce(s)
human, rat
E2250
Ellagic acid, ≥95% (HPLC), powder, from tree bark,
Espèce(s)
human, rat
T182
Tyrphostin A9, solid,
Espèce(s)
mouse, human
SML2589
Dasatinib, ≥98% (HPLC),
Espèce(s)
human

Kits

Référence du produit
Description
Espèce(s)
20-121
Src Kinase Reaction Buffer, ,
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
14-326-M
Src Protein, active, 10 µg, Active, N-Terminal His6-tagged, recombinant, full-length, human Src. For use in Kinase Assays.,
Espèce(s)
human
S1076
SRC, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
S5564
SRC N1 human, ≥60% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Espèce(s)
human
14-748-M
Src (T341M) Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, full-length human Src, containing the T341M mutation. For use in Kinase Assays.,
Espèce(s)
human
14-746-M
Src (1-530) Protein, active, 10 µg, ,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EMU071351
MISSION® esiRNA, targeting mouse Src,
Espèce(s)
mouse

Small Molecule - Substrate

Référence du produit
Description
Espèce(s)
12-140
Src Substrate Peptide, Src Substrate Peptide primarily used in Kinase Assays.,
Espèce(s)
human