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Merck

RFXAP

regulatory factor X-associated protein

Synonymes:
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5994) Summary: Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(170767) regulatory factor X-associated protein
  • Rat(499617) regulatory factor X-associated protein
  • Zebrafish(100006212) regulatory factor X-associated protein
  • dog(607367) regulatory factor X-associated protein
  • domestic guinea pig(100717309) regulatory factor X-associated protein
  • cow(540760) regulatory factor X-associated protein
  • naked mole-rat(101719989) regulatory factor X-associated protein
  • domestic cat(101088294) regulatory factor X-associated protein
  • chicken(418899) regulatory factor X-associated protein

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-RFXAP antibody produced in mouse, clone 1B5, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
Anti-RFXAP antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
western blot
Anti-RFXAP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-RFXAP antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Rfxap,
Espèce(s)
mouse