Accéder au contenu
Merck

RASSF1

Ras association (RalGDS/AF-6) domain family member 1

Synonymes:
123F2, NORE2A, RASSF1A, RDA32, REH3P21
Espèce(s):
Human RASSF1 (11186), Mouse Rassf1 (56289), Rat Rassf1 (363140), domestic cat RASSF1 (101094657), naked mole-rat Rassf1 (101707605), Zebrafish rassf1 (447811), chicken RASSF1 (101665483), chicken RASSF1 (101750777), dog RASSF1 (607929), domestic guinea pig Rassf1 (100717305) ...Plus
ID UniProtKB:
Q9NS23, B7ZLL1, O14571, O60539, O60710, Q0VGC6, Q5TZT2, Q9HB04
ID du gène:
  • Human(11186) Summary: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011]
  • Mouse(56289) Ras association (RalGDS/AF-6) domain family member 1
  • Rat(363140) Ras association (RalGDS/AF-6) domain family member 1
  • domestic cat(101094657) Ras association (RalGDS/AF-6) domain family member 1
  • naked mole-rat(101707605) Ras association (RalGDS/AF-6) domain family member 1
  • Zebrafish(447811) Ras association (RalGDS/AF-6) domain family 1
  • chicken(101665483) Ras association (RalGDS/AF-6) domain family member 1
  • chicken(101750777) Ras association (RalGDS/AF-6) domain family member 1
  • dog(607929) Ras association (RalGDS/AF-6) domain family member 1
  • domestic guinea pig(100717305) Ras association (RalGDS/AF-6) domain family member 1
  • cow(510276) Ras association (RalGDS/AF-6) domain family member 1
  • sheep(100302080) Ras association (RalGDS/AF-6) domain family member 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA040735
Anti-RASSF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
ABS1484
Anti-RASSF1, from rabbit, purified by affinity chromatography,
Espèces réactives
human, rat
Application
flow cytometry
immunohistochemistry
western blot
MABC112
Anti-RASSF1 Antibody, clone 5C9.1, clone 5C9.1, from mouse,
Espèces réactives
human
Application
immunohistochemistry
western blot

esiRNA

Référence du produit
Description
Espèce(s)
EMU038511
MISSION® esiRNA, targeting mouse Rassf1,
Espèce(s)
mouse
EHU088291
MISSION® esiRNA, targeting human RASSF1,
Espèce(s)
human