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Merck

POLD2

polymerase (DNA directed), delta 2, accessory subunit

Synonymes:
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5425) Summary: This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Mar 2012]
  • Mouse(18972) polymerase (DNA directed), delta 2, regulatory subunit
  • Rat(289758) polymerase (DNA directed), delta 2, accessory subunit
  • domestic cat(101095089) polymerase (DNA directed), delta 2, accessory subunit
  • dog(482686) polymerase (DNA directed), delta 2, accessory subunit
  • cow(281991) polymerase (DNA directed), delta 2, regulatory subunit 50kDa
  • sheep(101117838) polymerase (DNA directed), delta 2, accessory subunit
  • Domestic Rabbit(100358263) polymerase (DNA directed), delta 2, accessory subunit
  • domestic guinea pig(100727561) polymerase (DNA directed), delta 2, accessory subunit
  • naked mole-rat(101722261) polymerase (DNA directed), delta 2, accessory subunit
  • chicken(100859398) polymerase (DNA directed), delta 2, accessory subunit
  • Thale Cress(818812) DNA polymerase delta subunit 2
  • Zebrafish(796456) polymerase (DNA directed), delta 2, regulatory subunit

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-POLD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-DNA polymerase δ p50 antibody, Rat monoclonal, clone PDK 7B4, purified from hybridoma cell culture,
Espèces réactives
human
Application
immunocytochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
Cytosine β-D-arabinofuranoside hydrochloride, crystalline,
Espèce(s)
human
Cytarabine, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Cytarabine, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Cytarabine, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Cytarabine, British Pharmacopoeia (BP) Reference Standard,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Pold2,
Espèce(s)
mouse
MISSION® esiRNA, targeting human POLD2,
Espèce(s)
human