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Merck

PDGFRA

platelet-derived growth factor receptor, alpha polypeptide

Synonymes:
CD140A, PDGFR-2, PDGFR2, RHEPDGFRA
Espèce(s):
Human PDGFRA (5156), Mouse Pdgfra (18595), Rat Pdgfra (25267), chicken PDGFRA (395509), domestic guinea pig Pdgfra (100726209), cow PDGFRA (282301), Zebrafish pdgfra (386856), domestic cat PDGFRA (101090765), sheep PDGFRA (101106012), dog PDGFRA (442860) ...Plus
ID UniProtKB:
P16234, B2RE69, E9PBH0, Q6P4H5, Q96KZ7, Q9UD28
ID du gène:
  • Human(5156) Summary: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
  • Mouse(18595) platelet derived growth factor receptor, alpha polypeptide
  • Rat(25267) platelet derived growth factor receptor, alpha polypeptide
  • chicken(395509) platelet-derived growth factor receptor, alpha polypeptide
  • domestic guinea pig(100726209) platelet-derived growth factor receptor, alpha polypeptide
  • cow(282301) platelet-derived growth factor receptor, alpha polypeptide
  • Zebrafish(386856) platelet derived growth factor receptor alpha
  • domestic cat(101090765) platelet-derived growth factor receptor, alpha polypeptide
  • sheep(101106012) platelet-derived growth factor receptor, alpha polypeptide
  • dog(442860) platelet-derived growth factor receptor, alpha polypeptide
  • Horse(100059815) platelet-derived growth factor receptor, alpha polypeptide
  • naked mole-rat(101697360) platelet-derived growth factor receptor, alpha polypeptide

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ELISA

Référence du produit
Description
Espèce(s)
RAB0399
Human PDGF R α  ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human
RAB0984
Phosphotyrosine PDGFRA / Platelet-derived Growth Factor Receptor Alpha ELISA Kit, ,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA004947
Anti-PDGFRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
CBL1366
Anticorps anti-CD140a, clone APA5, clone APA5, Chemicon®, from rat,
Espèces réactives
mouse
Application
ELISA
flow cytometry
immunohistochemistry
western blot
WH0005156M1
Monoclonal Anti-PDGFRA antibody produced in mouse, clone 2D2-1A11, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
proximity ligation assay
western blot
SAB4502142
Anti-PDGFR α antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB4700454
Monoclonal Anti-CD140a antibody produced in mouse, clone 16A1, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
flow cytometry

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
T182
Tyrphostin A9, solid,
Espèce(s)
mouse, human
CDS023580
Pazopanib, ,
Espèce(s)
human
594687
α-Sexithiophene, ,
Espèce(s)
human, rat

Proteins

Référence du produit
Description
Espèce(s)
P3076
Platelet-Derived Growth Factor-AA human, PDGF-AA, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Espèce(s)
human
14-467-M
PDGFRα Protein, active, 50 µg, Active, recombinant human PDGFRα, residues 550-end, containing an N-terminal His6-tag, for use in Kinase Assays.,
Espèce(s)
human
D0946
PDGFRα (550-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
14-735-M
PDGFR α (550-end, V561D) Protein, active human, 250 µg, ,
Espèce(s)
human
SRP5254
PDGFR-α, active, GST tagged from mouse, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
mouse

esiRNA

Référence du produit
Description
Espèce(s)
EMU045101
MISSION® esiRNA, targeting mouse Pdgfra,
Espèce(s)
mouse
EHU006141
MISSION® esiRNA, targeting human PDGFRA,
Espèce(s)
human