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Merck

P2RX1

purinergic receptor P2X, ligand-gated ion channel, 1

Synonymes:
P2X1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5023) Summary: The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis. [provided by RefSeq, Jun 2013]
  • Mouse(18436) purinergic receptor P2X, ligand-gated ion channel, 1
  • Rat(25505) purinergic receptor P2X, ligand-gated ion channel, 1
  • Domestic Rabbit(100350587) purinergic receptor P2X, ligand-gated ion channel, 1
  • domestic cat(101091060) purinergic receptor P2X, ligand-gated ion channel, 1
  • Horse(100060689) purinergic receptor P2X, ligand-gated ion channel, 1
  • cow(514898) purinergic receptor P2X, ligand-gated ion channel, 1
  • domestic guinea pig(100727772) purinergic receptor P2X, ligand-gated ion channel, 1
  • sheep(101101902) purinergic receptor P2X, ligand-gated ion channel, 1
  • Zebrafish(387296) purinergic receptor P2X, ligand-gated ion channel, 1
  • chicken(395190) purinergic receptor P2X, ligand-gated ion channel, 1
  • dog(491223) purinergic receptor P2X, ligand-gated ion channel, 1
  • naked mole-rat(101722936) purinergic receptor P2X, ligand-gated ion channel, 1

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
α,β-Methyleneadenosine 5′-triphosphate lithium salt, ≥93% (HPLC), solid,
Espèce(s)
human

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Reactive Blue 4, Dye content 35 %,
Espèce(s)
rat
NF 023 hydrate, ≥98% (HPLC), solid,
Espèce(s)
human
Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate, solid, ≥98% (HPLC),
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-P2RX1 antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
dog, horse, human
Application
immunohistochemistry
western blot
Anti-P2RX1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-P2Rx1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
Anti-P2X1 Purinergic Receptor antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Espèces réactives
human, rat
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Suramin sodium salt, ≥98% (TLC),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human P2RX1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse P2rx1,
Espèce(s)
mouse