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Merck

NQO1

NAD(P)H dehydrogenase, quinone 1

Synonymes:
DHQU, DIA4, DTD, NMOR1, NMORI, QR1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1728) Summary: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(18104) NAD(P)H dehydrogenase, quinone 1
  • Rat(24314) NAD(P)H dehydrogenase, quinone 1
  • chicken(769737) NAD(P)H dehydrogenase, quinone 1
  • domestic guinea pig(100135582) NAD(P)H dehydrogenase, quinone 1
  • domestic cat(101097859) NAD(P)H dehydrogenase, quinone 1
  • Zebrafish(322506) NAD(P)H dehydrogenase, quinone 1
  • cow(519632) NAD(P)H dehydrogenase, quinone 1
  • sheep(101121876) NAD(P)H dehydrogenase, quinone 1
  • naked mole-rat(101711262) NAD(P)H dehydrogenase, quinone 1
  • dog(610935) NAD(P)H dehydrogenase, quinone 1

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ELISA

Référence du produit
Description
Espèce(s)
Human NQO-1 ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-NQO1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-NQO1 Antibody, clone 1D12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-NQO1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse
Application
western blot
Anti-NQO1 antibody produced in rabbit, ,
Espèces réactives
human, mouse
Application
immunofluorescence
western blot
Anti-NQO1 Rabbit pAb, liquid, Calbiochem®,
Espèces réactives
human, mouse
Application

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Menadione, crystalline,
Espèce(s)
human
Menadione, meets USP testing specifications,
Espèce(s)
human
Menadione (K3), analytical standard,
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
DT Diaphorase (NQO1) human, lyophilized powder, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Espèce(s)
human
NQO1 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Nqo1,
Espèce(s)
mouse
MISSION® esiRNA, targeting human NQO1,
Espèce(s)
human