MRE11A
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
- Human(4361) Summary: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(17535) meiotic recombination 11 homolog A (S. cerevisiae)
- Rat(64046) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
- domestic guinea pig(100721147) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
- naked mole-rat(101709211) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
- Domestic Rabbit(100356946) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
- sheep(101114806) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
- Horse(100060936) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
- domestic cat(101086923) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
- dog(494006) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
- Zebrafish(406637) meiotic recombination 11 homolog A (S. cerevisiae)
- chicken(395555) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
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