MAPK1
mitogen-activated protein kinase 1
Synonymes:
ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
Espèce(s):
Human MAPK1 (5594), Mouse Mapk1 (26413), Rat Mapk1 (116590), chicken MAPK1 (373953), Zebrafish mapk1 (360144), dog MAPK1 (477575), domestic cat MAPK1 (101087614), sheep MAPK1 (101115485), cow MAPK1 (327672), naked mole-rat Mapk1 (101706099)
ID UniProtKB:
ID du gène:
- Human(5594) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008]
- Mouse(26413) mitogen-activated protein kinase 1
- Rat(116590) mitogen activated protein kinase 1
- chicken(373953) mitogen-activated protein kinase 1
- Zebrafish(360144) mitogen-activated protein kinase 1
- dog(477575) mitogen-activated protein kinase 1
- domestic cat(101087614) mitogen-activated protein kinase 1
- sheep(101115485) mitogen-activated protein kinase 1
- cow(327672) mitogen-activated protein kinase 1
- naked mole-rat(101706099) mitogen-activated protein kinase 1
- domestic guinea pig(100715180) mitogen-activated protein kinase 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Référence du produit
Description
Espèce(s)
Cell-Based ELISA for detecting phospho-ERK1 / 2 (pThr202 / pTyr204) in cultured cell lines, 96 assays,
Espèce(s)
mouse, rat, human
Cell-Based ELISA Sampler Kit for detecting phospho-ERK1/2 (pThr202/pTyr204), phospho-JNK (pThr183/pTyr185), and phospho-p38 MAPK (pThr180/pTyr182) in cultured cell lines, 192 assays,
Espèce(s)
rat, human, mouse
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-MAPK 1/2 Antibody, from rabbit,
Espèces réactives
bovine, canine, human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Milli-Mark® Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate, Milli-Mark®, from rabbit,
Espèces réactives
human
Application
flow cytometry
Anti-ERK2 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anticorps anti-phospho-MAP Kinase1/2, clone 12D4, Upstate®, from mouse,
Espèces réactives
avian, canine, human, mouse, rat
Application
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-MAPK1 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
western blot
Small Molecule - Inhibitor
Proteins
Référence du produit
Description
Espèce(s)
ERK2, active, GST tagged human, recombinant, expressed in E. coli, PRECISIO® Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
esiRNA
Référence du produit
Description
Espèce(s)