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Merck

MAP3K14

mitogen-activated protein kinase kinase kinase 14

Synonymes:
FTDCR1B, HS, HSNIK, NIK
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(9020) Summary: This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]
  • Mouse(53859) mitogen-activated protein kinase kinase kinase 14
  • Rat(360640) mitogen-activated protein kinase kinase kinase 14
  • dog(490926) mitogen-activated protein kinase kinase kinase 14
  • chicken(419964) mitogen-activated protein kinase kinase kinase 14
  • sheep(101118799) mitogen-activated protein kinase kinase kinase 14
  • Domestic Rabbit(100351032) mitogen-activated protein kinase kinase kinase 14
  • cow(508367) mitogen-activated protein kinase kinase kinase 14
  • Horse(100050140) mitogen-activated protein kinase kinase kinase 14
  • naked mole-rat(101703313) mitogen-activated protein kinase kinase kinase 14
  • domestic guinea pig(100719582) mitogen-activated protein kinase kinase kinase 14
  • domestic cat(101083468) mitogen-activated protein kinase kinase kinase 14

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Antibodies

Référence du produit
Description
Espèces réactives
Application
ANTI-NIK (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human, rat
Application
immunohistochemistry
western blot
Anti-MAP3K14 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
proximity ligation assay

western blot
Anti-NIK Antibody, CT, Chemicon®, from rabbit,
Espèces réactives
human
Application
western blot
Anti-MAP3K14 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, canine, guinea pig, horse, human, mouse, pig, rabbit
Application
western blot

Proteins

Référence du produit
Description
Espèce(s)
MAP3K14(NIK) Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human MAP3K14,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Map3k14,
Espèce(s)
mouse