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IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

Synonymes:
IMPD2, IMPDH-II
Espèce(s):
Human IMPDH2 (3615), Mouse Impdh2 (23918), Rat Impdh2 (301005), dog IMPDH2 (476630), Zebrafish impdh2 (317745), domestic guinea pig Impdh2 (100730768), naked mole-rat Impdh2 (101701391), domestic cat IMPDH2 (101080693), cow IMPDH2 (511969), sheep IMPDH2 (101107823) ...Plus
ID UniProtKB:
P12268, Q6LEF3
ID du gène:
  • Human(3615) Summary: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
  • Mouse(23918) inosine 5'-phosphate dehydrogenase 2
  • Rat(301005) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • dog(476630) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Zebrafish(317745) IMP (inosine monophosphate) dehydrogenase 2
  • domestic guinea pig(100730768) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • naked mole-rat(101701391) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • domestic cat(101080693) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • cow(511969) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • sheep(101107823) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Domestic Rabbit(100355621) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • chicken(416058) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Horse(100063255) IMP (inosine 5'-monophosphate) dehydrogenase 2

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Antibodies

Numéro du produit
Description
Espèces réactives
Application
HPA001400
Anti-IMPDH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
WH0003615M1
Monoclonal Anti-IMPDH2 antibody produced in mouse, clone 1E12-B6, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunoprecipitation (IP)
western blot
ST1578
Anti-IMPDH2 Mouse mAb (1E12-B6), liquid, clone 1E12-B6, Calbiochem®,
Espèces réactives
human
Application
SAB6012122
Anti IMPDH2 Antibody, clone 23GB6670, Rabbit Monoclonal, clone 23GB6670, recombinant rabbit monoclonal, expressed in HEK293 cells,
Espèces réactives
human, rat
Application
flow cytometry
western blot
AV54366
Anti-IMPDH2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
N4505
β-Nicotinamide adenine dinucleotide, reduced dipotassium salt, ,
Espèce(s)
human
A4882
6-Thioguanine, ≥98%,
Espèce(s)
human
M5255
Mycophenolic acid, ≥98%,
Espèce(s)
human
R9644
Ribavirin, antiviral,
Espèce(s)
human
SML0284
Mycophenolate mofetil, ≥98% (HPLC),
Espèce(s)
human

Proteins

Numéro du produit
Description
Espèce(s)
I1782
Inosine Monophosphate Dehydrogenase Type II human, recombinant, expressed in E. coli,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
EHU027541
MISSION® esiRNA, targeting human IMPDH2,
Espèce(s)
human
EMU094871
MISSION® esiRNA, targeting mouse Impdh2,
Espèce(s)
mouse