IDH2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
Synonymes:
D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH
Espèce(s):
Human IDH2 (3418), Mouse Idh2 (269951), Rat Idh2 (361596), Thale Cress IDH2 (816218), Zebrafish idh2 (386951), dog IDH2 (479043), chicken IDH2 (431056), Domestic Rabbit IDH2 (100340796), sheep IDH2 (101102843), cow IDH2 (327669) ...Plus
ID UniProtKB:
ID du gène:
- Human(3418) Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeq, Jul 2008]
- Mouse(269951) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- Rat(361596) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- Thale Cress(816218) Isocitrate dehydrogenase [NAD] regulatory subunit 2
- Zebrafish(386951) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- dog(479043) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- chicken(431056) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- Domestic Rabbit(100340796) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- sheep(101102843) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- cow(327669) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- domestic cat(101082315) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- naked mole-rat(101708667) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- domestic guinea pig(100726681) isocitrate dehydrogenase 2 (NADP+), mitochondrial
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-IDH2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
bovine, canine, human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-IDH2 antibody produced in mouse, clone 5F11, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-IDH2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-IDH2 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-IDH2 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Kits
Référence du produit
Description
Espèce(s)
Proteins
Référence du produit
Description
Espèce(s)