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Merck

GRIN2D

glutamate receptor, ionotropic, N-methyl D-aspartate 2D

Synonymes:
EB11, GluN2D, NMDAR2D, NR2D
Espèce(s):
Human GRIN2D (2906), Mouse Grin2d (14814), Rat Grin2d (24412), cow GRIN2D (618181), domestic cat GRIN2D (101095061), naked mole-rat Grin2d (101710918), domestic guinea pig Grin2d (100731717), dog GRIN2D (484405), sheep GRIN2D (101105943)
ID UniProtKB:
O15399
ID du gène:
  • Human(2906) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010]
  • Mouse(14814) glutamate receptor, ionotropic, NMDA2D (epsilon 4)
  • Rat(24412) glutamate receptor, ionotropic, N-methyl D-aspartate 2D
  • cow(618181) glutamate receptor, ionotropic, N-methyl D-aspartate 2D
  • domestic cat(101095061) glutamate receptor, ionotropic, N-methyl D-aspartate 2D
  • naked mole-rat(101710918) glutamate receptor, ionotropic, N-methyl D-aspartate 2D
  • domestic guinea pig(100731717) glutamate receptor, ionotropic, N-methyl D-aspartate 2D
  • dog(484405) glutamate receptor, ionotropic, N-methyl D-aspartate 2D
  • sheep(101105943) glutamate receptor, ionotropic, N-methyl D-aspartate 2D

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Small Molecule - Agonist

Numéro du produit
Description
Espèce(s)
T2269
L-Tyrosine disodium salt hydrate, ≥98% (HPLC), powder,
Espèce(s)
mouse, rat, human
C3909
D-Cycloserine, synthetic,
Espèce(s)
human
M3262
N-Methyl-D-aspartic acid, ≥98% (TLC), solid,
Espèce(s)
human, rat
C6880
D-Cycloserine, ,
Espèce(s)
human, mouse, rat
A5930
N-Acetyl-Asp-Glu, ≥97% (TLC),
Espèce(s)
mouse, human, rat

Small Molecule - Allosteric Modulator

Numéro du produit
Description
Espèce(s)
A6981
Acamprosate calcium, ≥98% (HPLC), powder,
Espèce(s)
human
1000554
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Espèce(s)
human
BP1172
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
Espèce(s)
human

Small Molecule - Antagonist

Numéro du produit
Description
Espèce(s)
A8054
D(−)-2-Amino-5-phosphonopentanoic acid, NMDA receptor antagonist,
Espèce(s)
mouse, rat
I2892
Ifenprodil (+)-tartrate salt, ,
Espèce(s)
human
A0384
Arcaine sulfate salt, ,
Espèce(s)
human
A1910
(±)-2-Amino-4-phosphonobutyric acid, solid,
Espèce(s)
rat, human
C104
(±)-CPP, solid,
Espèce(s)
rat, human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
MAB5578
Anti-NMDAR2D Antibody, ascites fluid, clone 1G9.39A5, Chemicon®,
Espèces réactives
human, mouse, rabbit, rat
Application
western blot
SAB4301024
Anti-GRIN2D antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry

Small Molecule - Blocker

Numéro du produit
Description
Espèce(s)
D8816
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Espèce(s)
human
A7127
Agmatine sulfate salt, ≥97%, powder,
Espèce(s)
human
75517
Orphenadrine hydrochloride, ≥98.0% (AT),
Espèce(s)
human
Y0001181
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Y0000100
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
P0547
Pentamidine isethionate salt, powder,
Espèce(s)
human
75517
Orphenadrine hydrochloride, ≥98.0% (AT),
Espèce(s)
human
Y0001181
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Y0000100
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
EHU044001
MISSION® esiRNA, targeting human GRIN2D,
Espèce(s)
human
EMU028921
MISSION® esiRNA, targeting mouse Grin2d,
Espèce(s)
mouse