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Merck

GLRB

glycine receptor, beta

Synonymes:
HKPX2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2743) Summary: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  • Mouse(14658) glycine receptor, beta subunit
  • Rat(25456) glycine receptor, beta
  • naked mole-rat(101709956) glycine receptor, beta
  • dog(475477) glycine receptor, beta
  • Horse(100061981) glycine receptor, beta
  • domestic cat(101088482) glycine receptor, beta
  • cow(281198) glycine receptor, beta
  • sheep(101109484) glycine receptor, beta
  • domestic guinea pig(100727431) glycine receptor, beta
  • chicken(422411) glycine receptor, beta

Custom & Knockdown Gene Products

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Small Molecule - Allosteric Modulator

Référence du produit
Description
Espèce(s)
Isoflurane, ,
Espèce(s)
human
Halothane, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-GLRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-Glycine Receptor Antibody, Chemicon®, from rabbit,
Espèces réactives
human, mouse, rat
Application
immunoprecipitation (IP)
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human GLRB,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Glrb,
Espèce(s)
mouse