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Merck

FMO5

flavin containing monooxygenase 5

Synonymes:
Espèce(s):
Human FMO5 (2330), Mouse Fmo5 (14263), Rat Fmo5 (246248), domestic guinea pig Fmo5 (100135521), cow FMO5 (788719), Domestic Rabbit FMO5 (100009064), Zebrafish fmo5 (794311), chicken FMO5 (100857694), domestic cat FMO5 (101092533), sheep FMO5 (101113713) ...Plus
ID UniProtKB:
P49326, B2RBG1, C9JJD1, Q8IV22
ID du gène:
  • Human(2330) Summary: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
  • Mouse(14263) flavin containing monooxygenase 5
  • Rat(246248) flavin containing monooxygenase 5
  • domestic guinea pig(100135521) flavin containing monooxygenase 5
  • cow(788719) flavin containing monooxygenase 5
  • Domestic Rabbit(100009064) flavin containing monooxygenase 5
  • Zebrafish(794311) flavin containing monooxygenase 5
  • chicken(100857694) flavin containing monooxygenase 5
  • domestic cat(101092533) flavin containing monooxygenase 5
  • sheep(101113713) flavin containing monooxygenase 5
  • Horse(100065455) flavin containing monooxygenase 5
  • dog(475819) flavin containing monooxygenase 5

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Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA012373
Anti-FMO5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
SAB1405823
Anti-FMO5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
SAB1410416
Anti-FMO5 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot

Proteins

Référence du produit
Description
Espèce(s)
F5178
Flavin-Containing Monooxygenase-5, Microsomes human, recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EHU030541
MISSION® esiRNA, targeting human FMO5,
Espèce(s)
human
EMU037151
MISSION® esiRNA, targeting mouse Fmo5,
Espèce(s)
mouse