FCAR
Fc fragment of IgA, receptor for
Synonymes:
CD89
Espèce(s):
Human FCAR (2204), Rat Fcar (365183), Horse FCAR (100050205), cow FCAR (503555), domestic guinea pig Fcar (100716057)
ID UniProtKB:
ID du gène:
- Human(2204) Summary: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Rat(365183) Fc fragment of IgA, receptor for
- Horse(100050205) Fc fragment of IgA, receptor for
- cow(503555) Fc fragment of IgA, receptor for
- domestic guinea pig(100716057) Fc fragment of IgA, receptor for
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ELISA
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Description
Espèce(s)
Antibodies
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Espèces réactives
Application
Monoclonal Anti-CD89 antibody produced in mouse, clone A59,
Espèces réactives
human, nonhuman primates
Application
flow cytometry
Anti-FCAR antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
esiRNA
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Espèce(s)