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Merck

ENPP2

ectonucleotide pyrophosphatase/phosphodiesterase 2

Synonymes:
ATX, ATX-X, AUTOTAXIN, LysoPLD, NPP2, PD-IALPHA, PDNP2
Espèce(s):
Human ENPP2 (5168), Mouse Enpp2 (18606), Rat Enpp2 (84050), dog ENPP2 (482026), chicken ENPP2 (420361), Zebrafish enpp2 (393575), naked mole-rat Enpp2 (101710936), domestic guinea pig Enpp2 (100722506), cow ENPP2 (532663), sheep ENPP2 (101120171) ...Plus
ID UniProtKB:
Q13822, A8UHA1, E9PHP7, Q13827, Q14555, Q15117, Q9UCQ8, Q9UCR0
ID du gène:
  • Human(5168) Summary: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]
  • Mouse(18606) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Rat(84050) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • dog(482026) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • chicken(420361) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Zebrafish(393575) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • naked mole-rat(101710936) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • domestic guinea pig(100722506) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • cow(532663) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • sheep(101120171) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • domestic cat(101097620) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Horse(100057101) ectonucleotide pyrophosphatase/phosphodiesterase 2

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Antibodies

Référence du produit
Description
Espèces réactives
Application
ABT28
Anti-Autotaxin Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
bovine, canine, human, mouse, rat
Application
immunohistochemistry
western blot
HPA053652
Anti-ENPP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
SAB1412735
Anti-ENPP2 antibody produced in mouse, purified immunoglobulin,
Espèces réactives
human
Application
western blot
SAB2700320
Anti-ENPP2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
western blot
MABT1350
Anti-Autotaxin (ENPP2) Antibody, clone 7A5, clone 7A5, from mouse,
Espèces réactives
human, mouse
Application
immunocytochemistry
immunohistochemistry
western blot

Proteins

Référence du produit
Description
Espèce(s)
SRP5361
ENPP2, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EHU073321
MISSION® esiRNA, targeting human ENPP2,
Espèce(s)
human
EMU038281
MISSION® esiRNA, targeting mouse Enpp2,
Espèce(s)
mouse