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Merck

DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

Synonymes:
DNMT3A2, M.HsaIIIA
Espèce(s):
Human DNMT3A (1788), Mouse Dnmt3a (13435), Rat Dnmt3a (444984), sheep DNMT3A (100500776), Domestic Rabbit DNMT3A (100344715), cow DNMT3A (359716), domestic cat DNMT3A (100510798), Horse DNMT3A (100055881), dog DNMT3A (482996), naked mole-rat Dnmt3a (101718745) ...Plus
ID UniProtKB:
Q9Y6K1, E9PEB8, Q86TE8, Q86XF5, Q8IZV0, Q8WXU9
ID du gène:
  • Human(1788) Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(13435) DNA methyltransferase 3A
  • Rat(444984) DNA (cytosine-5-)-methyltransferase 3 alpha
  • sheep(100500776) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Domestic Rabbit(100344715) DNA (cytosine-5-)-methyltransferase 3 alpha
  • cow(359716) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic cat(100510798) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Horse(100055881) DNA (cytosine-5-)-methyltransferase 3 alpha
  • dog(482996) DNA (cytosine-5-)-methyltransferase 3 alpha
  • naked mole-rat(101718745) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic guinea pig(100721625) DNA (cytosine-5-)-methyltransferase 3 alpha
  • chicken(421991) DNA (cytosine-5-)-methyltransferase 3 alpha

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Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA026588
Anti-DNMT3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
SAB2501730
Anti-DNMT3A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
bovine, human, mouse, rat
Application
ELISA
western blot
SAB5701326
Anti- DNMT3A antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
SAB5700766
Anti-DNMT3A antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
A3656
5-Aza-2′-deoxycytidine, ≥97%,
Espèce(s)
human
1045520
Azacitidine, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
A1287
5-Azacytidine, Hybri-Max™, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma,
Espèce(s)
human
PHR1911
Azacitidine, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
A2385
5-Azacytidine, ≥98% (HPLC),
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
SRP0128
DNMT3a Active human, recombinant, expressed in baculovirus infected insect cells,
Espèce(s)
human
SRP0396
DNMT3A/DNMT3L active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EHU123831
MISSION® esiRNA, targeting human DNMT3A,
Espèce(s)
human
EMU028371
MISSION® esiRNA, targeting mouse Dnmt3a,
Espèce(s)
mouse