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Merck

DDR2

discoidin domain receptor tyrosine kinase 2

Synonymes:
MIG20a, NTRKR3, TKT, TYRO10
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4921) Summary: Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  • Mouse(18214) discoidin domain receptor family, member 2
  • Rat(685781) discoidin domain receptor tyrosine kinase 2
  • chicken(396404) discoidin domain receptor tyrosine kinase 2
  • dog(478987) discoidin domain receptor tyrosine kinase 2
  • Zebrafish(559428) discoidin domain receptor family, member 2
  • domestic guinea pig(100729537) discoidin domain receptor tyrosine kinase 2
  • sheep(101109754) discoidin domain receptor tyrosine kinase 2
  • naked mole-rat(101712349) discoidin domain receptor tyrosine kinase 2
  • cow(533523) discoidin domain receptor tyrosine kinase 2
  • Horse(100058300) discoidin domain receptor tyrosine kinase 2
  • domestic cat(101085267) discoidin domain receptor tyrosine kinase 2

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ELISA

Référence du produit
Description
Espèce(s)
Phosphotyrosine DDR2 / Discoidin domain-containing Receptor 2 ELISA Kit, ,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-DDR2 Antibody, clone 1M8U7, Rabbit Monoclonal, ,
Espèces réactives
human, rat
Application
western blot
Monoclonal Anti-DDR2 antibody produced in mouse, clone 3B11E4, ascites fluid,
Espèces réactives
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
MONOCLONAL ANTI-DDR2 antibody produced in mouse, clone 484CT5.5.4, crude ascites, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-DDR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Ddr2,
Espèce(s)
mouse
MISSION® esiRNA, targeting human DDR2,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Ddr2,
Espèce(s)
mouse