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Merck

CHRM5

cholinergic receptor, muscarinic 5

Synonymes:
HM5
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1133) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008]
  • Mouse(213788) cholinergic receptor, muscarinic 5
  • Rat(53949) cholinergic receptor, muscarinic 5
  • naked mole-rat(101719201) cholinergic receptor, muscarinic 5
  • Domestic Rabbit(100342984) cholinergic receptor, muscarinic 5
  • dog(487472) cholinergic receptor, muscarinic 5
  • Horse(100057856) cholinergic receptor, muscarinic 5
  • cow(281686) cholinergic receptor, muscarinic 5
  • sheep(101110766) cholinergic receptor, muscarinic 5
  • domestic cat(101097246) cholinergic receptor, muscarinic 5
  • chicken(428881) cholinergic receptor, muscarinic 5
  • domestic guinea pig(100379240) cholinergic receptor, muscarinic 5

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
Pilocarpine hydrochloride, ≥99% (titration), powder,
Espèce(s)
human
Acetyl-β-methylcholine chloride, ≥98% (TLC), powder,
Espèce(s)
human
Pilocarpine nitrate salt, ≥98% (HPLC),
Espèce(s)
human
Oxotremorine M, solid,
Espèce(s)
human
(±)-Muscarine chloride hydrate, ≥98% (HPLC),
Espèce(s)
human

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
(−)-Scopolamine hydrobromide trihydrate, ≥98% (HPLC), powder,
Espèce(s)
human
Atropine sulfate salt monohydrate, ≥97% (TLC), crystalline,
Espèce(s)
human
(−)-Scopolamine methyl bromide, ≥98% (HPLC), powder,
Espèce(s)
human
(−)-Scopolamine N-butyl bromide, ≥98% (TLC), powder,
Espèce(s)
human
Oxybutynin chloride, ≥98% (TLC), powder,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-CHRM5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-CHRM5, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
Anti-CHRM5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Amitriptyline hydrochloride, ≥98% (TLC), powder,
Espèce(s)
human
Doxepin hydrochloride, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Espèce(s)
human
Harmaline, ≥95%,
Espèce(s)
human, rat

Small Molecule - Ligand

Référence du produit
Description
Espèce(s)
Aminobenztropine, solid,
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
ChemiScreen Membrane Preparation
Recombinant Human M5 Muscarinic Acetylcholine Receptor
, Human M5 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CHRM5,
Espèce(s)
human