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Merck

CENPA

centromere protein A

Synonymes:
CENP-A, CenH3
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1058) Summary: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(12615) centromere protein A
  • Rat(298850) centromere protein A
  • chicken(100113359) centromere protein A
  • dog(475692) centromere protein A
  • domestic cat(101082304) centromere protein A
  • cow(613898) centromere protein A
  • Zebrafish(100302659) histone H3-like centromeric protein A
  • naked mole-rat(101700835) centromere protein A
  • domestic guinea pig(100724949) centromere protein A
  • sheep(101110750) centromere protein A

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-CENPA antibody produced in mouse, clone 1D4-1A3, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
Anti-CENP-A Antibody, Upstate®, from rabbit,
Espèces réactives
human
Application
western blot
Anti-Centromeric Protein A antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunofluorescence

immunohistochemistry
Anti-CENP-A antibody produced in rabbit, ~2 mg/mL, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-phospho-CENP-A (Ser7) Antibody, clone NL41, rabbit monoclonal, culture supernatant, clone NL41, Upstate®,
Espèces réactives
human
Application
immunocytochemistry
multiplexing

western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CENPA,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Cenpa,
Espèce(s)
mouse