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Merck

CDH1

cadherin 1, type 1, E-cadherin (epithelial)

Synonymes:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
  • Mouse(12550) cadherin 1
  • Rat(83502) cadherin 1
  • dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
  • chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
  • naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
  • Zebrafish(114424) cadherin 1, epithelial
  • cow(282637) cadherin 1, type 1, E-cadherin (epithelial)

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Mouse E-Cadherin ELISA Kit, for serum, plasma and cell culture supernatant,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-E-Cadherin Antibody, serum, Upstate®,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-E-cadherin antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-E-Cadherin antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-E-Cadherin Antibody, clone 67A4, Azide Free, clone 67A4, Chemicon®, from mouse,
Espèces réactives
human
Application
flow cytometry
immunofluorescence
Anti-E-Cadherin/CD324 Antibody, clone 19A11, ,
Espèces réactives
canine, human
Application
ELISA
immunocytochemistry

inhibition assay

western blot

Cell Lines

Numéro du produit
Description
Espèce(s)
MCF10A CELLS CDH1 (-/-), ,
Espèce(s)
human

Proteins

Numéro du produit
Description
Espèce(s)
E-Cadherin human, recombinant, expressed in E. coli, 0.5 mg protein/mL,
Espèce(s)
human
E-Cadherin/Fc Chimera from mouse, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Espèce(s)
mouse

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CDH1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Cdh1,
Espèce(s)
mouse