CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
- Human(815) Summary: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]
- Mouse(12322) calcium/calmodulin-dependent protein kinase II alpha
- Rat(25400) calcium/calmodulin-dependent protein kinase II alpha
- Zebrafish(550436) calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
- Domestic Rabbit(100341507) calcium/calmodulin-dependent protein kinase II alpha
- dog(612941) calcium/calmodulin-dependent protein kinase II alpha
- domestic cat(101084342) calcium/calmodulin-dependent protein kinase II alpha
- cow(530719) calcium/calmodulin-dependent protein kinase II alpha
- naked mole-rat(101722229) calcium/calmodulin-dependent protein kinase II alpha
- domestic guinea pig(100727059) calcium/calmodulin-dependent protein kinase II alpha
- Horse(100071654) calcium/calmodulin-dependent protein kinase II alpha
- chicken(374175) calcium/calmodulin-dependent protein kinase II alpha
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