BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
Synonymes:
BMPR-II, BMPR3, BMR2, BRK-3, PPH1, T-ALK
Espèce(s):
Human BMPR2 (659), Mouse Bmpr2 (12168), Rat Bmpr2 (140590), cow BMPR2 (407127), naked mole-rat Bmpr2 (101701138), Domestic Rabbit BMPR2 (100350246), sheep BMPR2 (101103793), domestic guinea pig Bmpr2 (100736232), chicken BMPR2 (374147), sheep BMPR2 (100294556) ...Plus
ID UniProtKB:
ID du gène:
- Human(659) Summary: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]
- Mouse(12168) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- Rat(140590) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- cow(407127) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- naked mole-rat(101701138) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- Domestic Rabbit(100350246) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- sheep(101103793) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- domestic guinea pig(100736232) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- chicken(374147) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- sheep(100294556) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- domestic cat(101096338) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- dog(478875) bone morphogenetic protein receptor, type II (serine/threonine kinase)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Référence du produit
Description
Espèce(s)
Human BMPR-II ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Espèce(s)
human
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-BMPR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-BMPR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-BMR2 Antibody, clone 3F6, ascites fluid, clone 3F6, from mouse,
Espèces réactives
human, monkey, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-BMPR2 antibody produced in mouse, clone 3F6, ascites fluid,
Espèces réactives
human, monkey, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Monoclonal Anti-BMPR2 antibody produced in mouse, clone 4A2, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
Proteins
Référence du produit
Description
Espèce(s)
BMPR2 (174-end), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human