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Merck

ATP1B2

ATPase, Na+/K+ transporting, beta 2 polypeptide

Synonymes:
AMOG
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(482) Summary: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 2 subunit. [provided by RefSeq, Jul 2008]
  • Mouse(11932) ATPase, Na+/K+ transporting, beta 2 polypeptide
  • Rat(24214) ATPase, Na+/K+ transporting, beta 2 polypeptide
  • Horse(100073014) ATPase, Na+/K+ transporting, beta 2 polypeptide
  • cow(282562) ATPase, Na+/K+ transporting, beta 2 polypeptide
  • naked mole-rat(101701421) ATPase, Na+/K+ transporting, beta 2 polypeptide
  • domestic guinea pig(100733951) ATPase, Na+/K+ transporting, beta 2 polypeptide
  • Domestic Rabbit(100009577) ATPase, Na+/K+ transporting, beta 2 polypeptide
  • dog(489479) ATPase, Na+/K+ transporting, beta 2 polypeptide
  • domestic cat(101100258) ATPase, Na+/K+ transporting, beta 2 polypeptide
  • sheep(101103490) ATPase, Na+/K+ transporting, beta 2 polypeptide

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-ATP1B2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-ATP1B2 antibody produced in mouse, clone 4E3, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
Anti-ATP1B2, affinity isolated antibody,
Espèces réactives
human, mouse
Application
western blot
Anti-ATP1B2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rat
Application
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Digitoxin, ≥92% (HPLC), powder,
Espèce(s)
human
Digoxin, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Digitoxin, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Digoxin, analytical standard,
Espèce(s)
human
Digoxin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ATP1B2,
Espèce(s)
human