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Merck

ATP1A3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

Synonymes:
AHC2, DYT12, RDP
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(478) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(232975) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • Rat(24213) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • domestic cat(101083636) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • Horse(100069796) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • dog(612463) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • chicken(396467) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • naked mole-rat(101721146) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • cow(282598) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • sheep(101103751) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • domestic guinea pig(100712985) ATPase, Na+/K+ transporting, alpha 3 polypeptide

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6, clone C464.6, Upstate®, from mouse,
Espèces réactives
xenopus, canine, human, monkey, mouse, pig, rabbit, rat, sheep
Application
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Na+/K+ ATPase β-1 Antibody, clone C464.8, clone C464.8, Upstate®, from mouse,
Espèces réactives
bovine, canine, human, rabbit, rat
Application
immunohistochemistry
western blot
Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6, Alexa Fluor 488, clone C464.6, Upstate®, from mouse,
Espèces réactives
xenopus, canine, human, monkey, mouse, pig, rabbit, rat
Application
flow cytometry
immunocytochemistry

western blot
Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6, Alexa Fluor 555, clone C464.6, Upstate®, from mouse,
Espèces réactives
xenopus, canine, human, monkey, mouse, pig, rabbit, rat, sheep
Application
flow cytometry
immunofluorescence

western blot
Anti-ATP1A3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Digitoxin, ≥92% (HPLC), powder,
Espèce(s)
human
Digoxin, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Digitoxin, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Digoxin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Digoxin, analytical standard,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Atp1a3,
Espèce(s)
mouse
MISSION® esiRNA, targeting human ATP1A3,
Espèce(s)
human