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Merck

ATF1

activating transcription factor 1

Synonymes:
EWS-ATF1, FUS/ATF-1, TREB36
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(466) Summary: This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq, Aug 2010]
  • Mouse(11908) activating transcription factor 1
  • Rat(315305) activating transcription factor 1
  • naked mole-rat(101726719) activating transcription factor 1
  • cow(506967) activating transcription factor 1
  • sheep(101117917) activating transcription factor 1
  • domestic cat(101088253) activating transcription factor 1
  • Zebrafish(325609) activating transcription factor 1
  • chicken(426873) activating transcription factor 1
  • domestic guinea pig(100719533) activating transcription factor 1
  • dog(486545) activating transcription factor 1

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-ATF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-ATF-1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
microarray
western blot
Anti-ATF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-ATF1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
dog, guinea pig, horse, human, rabbit, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-ATF1 antibody produced in mouse, clone 3E7, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry

western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ATF1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Atf1 (2),
Espèce(s)
mouse
MISSION® esiRNA, targeting mouse Atf1 (1),
Espèce(s)
mouse