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Merck

ANTXR1

anthrax toxin receptor 1

Synonymes:
ATR, GAPO, TEM8
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(84168) Summary: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
  • Mouse(69538) anthrax toxin receptor 1
  • Rat(362393) anthrax toxin receptor 1
  • naked mole-rat(101701494) anthrax toxin receptor 1
  • domestic guinea pig(100728514) anthrax toxin receptor 1
  • sheep(101108204) anthrax toxin receptor 1
  • Domestic Rabbit(100357637) anthrax toxin receptor 1
  • cow(616010) anthrax toxin receptor 1
  • domestic cat(101092930) anthrax toxin receptor 1
  • Horse(100061334) anthrax toxin receptor 1
  • dog(612601) anthrax toxin receptor 1
  • chicken(428199) anthrax toxin receptor 1

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-ANTXR1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-ATR antibody produced in rabbit, purified antibody (Ion exchange),
Espèces réactives
Application
immunofluorescence
immunohistochemistry

western blot
Anti-Phospho-ANTXR1-pY382 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
dot blot
Anti-ATR (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunocytochemistry

immunofluorescence

western blot
Anti-ATR Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
human
Application
immunocytochemistry
immunohistochemistry

western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Antxr1,
Espèce(s)
mouse
MISSION® esiRNA, targeting human ANTXR1,
Espèce(s)
human