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Merck

ABCD1

ATP-binding cassette, sub-family D (ALD), member 1

Synonymes:
ABC42, ALD, ALDP, AMN
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(215) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008]
  • Mouse(11666) ATP-binding cassette, sub-family D (ALD), member 1
  • Rat(363516) ATP-binding cassette, subfamily D (ALD), member 1
  • sheep(101122673) ATP-binding cassette, sub-family D (ALD), member 1
  • Domestic Rabbit(100328741) ATP-binding cassette, sub-family D (ALD), member 1
  • Zebrafish(566367) ATP-binding cassette, sub-family D (ALD), member 1
  • dog(612520) ATP-binding cassette, sub-family D (ALD), member 1
  • domestic cat(101088223) ATP-binding cassette, sub-family D (ALD), member 1
  • cow(515178) ATP-binding cassette, sub-family D (ALD), member 1
  • naked mole-rat(101720585) ATP-binding cassette, sub-family D (ALD), member 1
  • domestic guinea pig(100713152) ATP-binding cassette, sub-family D (ALD), member 1

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Adrenoleukodystrophy Protein Antibody, a.a. 279-482, clone 2AL-1D6, ascites fluid, clone 2AL-1D6, Chemicon®,
Espèces réactives
human
Application
ELISA
immunocytochemistry

immunohistochemistry

western blot
Monoclonal Anti-ABCD1 antibody produced in mouse, clone 4B5, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
Anti-ABCD1, affinity isolated antibody,
Espèces réactives
human, mouse
Application
immunohistochemistry
Anti-Adrenoleukodystrophy Protein Antibody, a.a. 495-648, clone 1AL-2B4, ascites fluid, clone 1AL-2B4, Chemicon®,
Espèces réactives
human
Application
ELISA
immunocytochemistry

immunohistochemistry

western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Abcd1,
Espèce(s)
mouse
MISSION® esiRNA, targeting human ABCD1,
Espèce(s)
human