ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Synonymes:
ABC30, CMOAT, DJS, MRP2, cMRP
Espèce(s):
Human ABCC2 (1244), Mouse Abcc2 (12780), Rat Abcc2 (25303), sheep ABCC2 (101119776), Horse ABCC2 (100060654), naked mole-rat Abcc2 (101716089), domestic guinea pig Abcc2 (100718828), cow ABCC2 (520925), domestic cat ABCC2 (101085924), dog ABCC2 (403632) ...Plus
ID UniProtKB:
ID du gène:
- Human(1244) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008]
- Mouse(12780) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- Rat(25303) ATP-binding cassette, subfamily C (CFTR/MRP), member 2
- sheep(101119776) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- Horse(100060654) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- naked mole-rat(101716089) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- domestic guinea pig(100718828) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- cow(520925) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- domestic cat(101085924) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- dog(403632) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- chicken(423828) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- Zebrafish(393561) ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-MRP2 Antibody, clone 1B2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, monkey
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-MRP2 Antibody, CT, clone M2 III-6, culture supernatant, clone M2 III-6, Chemicon®,
Espèces réactives
human
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ABCC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-MRP2 Antibody, clone M2 I-4, culture supernatant, clone M2 I-4, Chemicon®,
Espèces réactives
human
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MRP2 antibody, Mouse monoclonal, clone CPR96, purified from hybridoma cell culture,
Espèces réactives
human
Application
ELISA
microarray
western blot
microarray
western blot
Cell Lines
Kits
Référence du produit
Description
Espèce(s)
esiRNA
Référence du produit
Description
Espèce(s)