LC/MS Analysis of Illicit Bath Salts on Ascentis® Express HILIC, Set 4
Materials
analytical column
Product No.
Description
Pricing
Application
Product No.
Description
Pricing
standard
Product No.
Description
Pricing
Buphedrone hydrochloride solution
1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®Mephedrone hydrochloride solution
1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®Methylone hydrochloride
1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®MDAI hydrochloride solution
100 μg/mL in acetonitrile: water (9:1) with 5% 1 M HCl (as free base), ampule of 1 mL, certified reference material, Cerilliant®Pyrovalerone hydrochloride solution
1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®N-Ethylcathinone hydrochloride solution
1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®CONDITIONS
column
Ascentis Express HILIC, 10 cm x 2.1 mm I.D., 2.7 μm particles (53939-U)
mobile phase
5 mM ammonium formate in [A] acetonitrile; [B] water; (98:2, A:B)
flow rate
0.6 mL/min
pressure
267 psi (18.4 bar)
column temp.
35 °C
detector
MS, ESI(+) TOF, Summed Ion Chromatogram
injection
2 μL
sample
500 ng/mL in acetonitrile
Description
Analysis Note
HILIC mode operation on an Ascentis Express column provided baseline resolution of these bath salts, including isobaric compounds. Ultra high purity solvents were used to supply low background interference and low particulate contaminants for robust; trouble-free operation. Cerilliant CRMs provided reliable identification and quantification.
Legal Information
Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany