Visualizing nanoparticle mobility in liquid at atomic resolution.

Visualizing nanoparticle mobility in liquid at atomic resolution.

Chemical communications (Cambridge, England) (2013-03-06)

Madeline J Dukes, Benjamin W Jacobs, David G Morgan, Harshad Hegde, Deborah F Kelly

ABSTRACT

Gold nanorods are widely known for their photothermal properties to treat solid tumors. Our work demonstrates the unrealized capacity to image these reagents in liquid at high resolution using Transmission Electron Microscopy (TEM). Here we perform the first atomic measurements of functionalized nanorods in solution while visualizing their dynamic behaviour with TEM.

MATERIALS

Product Number

Brand

Product Description

334103

Sigma-Aldrich

Silicon nitride, powder, ≥99.9% trace metals basis

325171

Sigma-Aldrich

Silicon nitride, predominantly α-phase, ≤10 micron

248622

Sigma-Aldrich

Silicon nitride, predominantly β-phase, ≤10micron primary particle size

636703

Sigma-Aldrich

Silicon nitride, nanopowder, <50 nm particle size (spherical), ≥98.5% trace metals basis