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  • Cuprizone-induced Demyelination in Mouse Brain is not due to Depletion of Copper.

Cuprizone-induced Demyelination in Mouse Brain is not due to Depletion of Copper.

ASN neuro (2022-09-18)
Megan L Morgan, Wulin Teo, Yda Hernandez, Craig Brideau, Karen Cummins, Hedwich F Kuipers, Peter K Stys
ABSTRACT

The demyelinating effects of CPZ are not due to Cu deficiency but are instead consistent with acute toxicity of a CPZ + Cu complex.