D167800
2,3-Dimethylmaleic anhydride
98%
Synonym(s):
Dimethylmaleic anhydride
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About This Item
Empirical Formula (Hill Notation):
C6H6O3
CAS Number:
Molecular Weight:
126.11
Beilstein:
112044
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
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Assay
98%
form
flakes
bp
223 °C (lit.)
mp
93-96 °C (lit.)
SMILES string
CC1=C(C)C(=O)OC1=O
InChI
1S/C6H6O3/c1-3-4(2)6(8)9-5(3)7/h1-2H3
InChI key
MFGALGYVFGDXIX-UHFFFAOYSA-N
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Kabrambam D Singh et al.
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Se Rim Yoon et al.
Journal of biomedical materials research. Part A, 100(8), 2027-2033 (2012-05-15)
A charge-converting and pH-dependent nanocarrier was achieved by conjugating 2,3-dimethylmaleic anhydride (DMMA) to the amino group of an octadecyl grafted poly (2-hydroxyethyl aspartamide) (PHEA-g-C(18)-NH(2)) backbone, thereby forming a spherical micelle. PHEA, a poly(amino acid)s derivative, was derived from poly(succinimide), which
S Tsunoda et al.
The Journal of pharmacology and experimental therapeutics, 290(1), 368-372 (1999-06-25)
We attempted to develop a novel method for the chemical modification of cytokines with synthetic polymers to increase in vivo therapeutic efficacy. A pH-reversible amino-protective reagent, dimethylmaleic anhydride (DMMAn), was used for polymer conjugation of tumor necrosis factor-alpha (TNF-alpha) with
C Vard et al.
The Journal of biological chemistry, 272(32), 20259-20262 (1997-08-08)
The acidic ribosomal proteins P1-P2 from rat liver were overproduced for the first time by expression of their cDNA in Escherichia coli. They were tested for their ability to reactivate inactive P1-P2-deficient core particles derived from 60 S ribosomal subunits
Enhanced activity of immobilized dimethylmaleic anhydride-protected poly- and monoclonal antibodies.
E Hadas et al.
Journal of chromatography, 510, 303-309 (1990-06-27)
The effect of reversible protection of the free amino groups of poly- and monoclonal antibodies by dimethylmaleic anhydride on their binding activity following immobilization onto various carriers was studied. The treatment with dimethylmaleic anhydride resulted in a 1.6-1.8-fold increase in
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