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Merck

SLC18A2

solute carrier family 18 (vesicular monoamine transporter), member 2

Synonyms:
SVAT, SVMT, VAT2, VMAT2
Species:
UniProtKB ID:
Gene ID:
  • Human(6571) Summary: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al., 1993 [PubMed 7905859]
  • Mouse(214084) solute carrier family 18 (vesicular monoamine), member 2
  • Rat(25549) solute carrier family 18 (vesicular monoamine transporter), member 2
  • Horse(100058805) solute carrier family 18 (vesicular monoamine), member 2
  • cow(282471) solute carrier family 18 (vesicular monoamine), member 2
  • domestic guinea pig(100719098) solute carrier family 18 (vesicular monoamine), member 2
  • domestic cat(101086507) solute carrier family 18 (vesicular monoamine), member 2
  • dog(486908) solute carrier family 18 (vesicular monoamine), member 2
  • naked mole-rat(101725597) solute carrier family 18 (vesicular monoamine), member 2
  • chicken(423921) solute carrier family 18 (vesicular monoamine), member 2
  • sheep(101104796) solute carrier family 18 (vesicular monoamine), member 2
  • Zebrafish(553304) solute carrier family 18 (vesicular monoamine), member 2

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SLC18A2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL12531, purified by using Protein A, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-SLC18A2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL13157, purified by using Protein A, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-SLC18A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-VMAT2/SLC18A2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, rat
Application
ELISA
immunohistochemistry

western blot
Anti-Vesicular Monoamine Transporter 2 Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Reserpine, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Species
human
Reserpine, crystallized, ≥99.0% (HPLC),
Species
human
Reserpine, phyproof® Reference Substance,
Species
human
Reserpine, United States Pharmacopeia (USP) Reference Standard,
Species
human
Reserpine, European Pharmacopoeia (EP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Slc18a2,
Species
mouse
MISSION® esiRNA, targeting human SLC18A2,
Species
human