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Merck

PTGDS

prostaglandin D2 synthase 21kDa (brain)

Synonyms:
L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2
Species:
UniProtKB ID:
Gene ID:
  • Human(5730) Summary: The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008]
  • Mouse(19215) prostaglandin D2 synthase (brain)
  • Rat(25526) prostaglandin D2 synthase (brain)
  • domestic cat(493852) prostaglandin D2 synthase 21kDa (brain)
  • domestic guinea pig(100732586) prostaglandin D2 synthase 21kDa (brain)
  • naked mole-rat(101699559) prostaglandin D2 synthase 21kDa (brain)
  • Horse(100067921) prostaglandin D2 synthase 21kDa (brain)
  • dog(403740) prostaglandin D2 synthase 21kDa (brain)
  • chicken(374110) prostaglandin D2 synthase 21kDa (brain)
  • sheep(443192) prostaglandin D2 synthase 21kDa (brain)
  • cow(286858) prostaglandin D2 synthase 21kDa (brain)

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Ptgds Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-PTGDS antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-PTGDS Antibody, from rabbit,
Species Reactivity
human, rhesus macaque
Application
immunohistochemistry
western blot
Anti-PTGDS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-PTGDS antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ptgds,
Species
mouse