NLRC4
NLR family, CARD domain containing 4
Synonyms:
CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, IPAF
Species:
Human NLRC4 (58484), Mouse Nlrc4 (268973), Rat Nlrc4 (298784), sheep NLRC4 (101104138), Horse NLRC4 (100070605), dog NLRC4 (100302328), domestic guinea pig Nlrc4 (100735110), naked mole-rat Nlrc4 (101712438), domestic cat NLRC4 (101087657), cow NLRC4 (512480)
UniProtKB ID:
Gene ID:
- Human(58484) Summary: In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM, Mar 2008]
- Mouse(268973) NLR family, CARD domain containing 4
- Rat(298784) NLR family, CARD domain containing 4
- sheep(101104138) NLR family, CARD domain containing 4
- Horse(100070605) NLR family, CARD domain containing 4
- dog(100302328) NLR family, CARD domain containing 4 pseudogene
- domestic guinea pig(100735110) NLR family, CARD domain containing 4
- naked mole-rat(101712438) NLR family, CARD domain containing 4
- domestic cat(101087657) NLR family, CARD domain containing 4
- cow(512480) NLR family, CARD domain containing 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NLRC4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Nlrc4 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Monoclonal Anti-CARD12 antibody produced in mouse, clone GT1387, affinity isolated antibody,
Species Reactivity
human
Application
western blot