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Merck

C1QC

complement component 1, q subcomponent, C chain

Synonyms:
C1Q-C, C1QG
Species:
UniProtKB ID:
Gene ID:
  • Human(714) Summary: This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12262) complement component 1, q subcomponent, C chain
  • Rat(362634) complement component 1, q subcomponent, C chain
  • naked mole-rat(101704347) complement component 1, q subcomponent, C chain
  • domestic guinea pig(100716082) complement component 1, q subcomponent, C chain
  • domestic cat(101094773) complement component 1, q subcomponent, C chain
  • dog(487382) complement component 1, q subcomponent, C chain
  • sheep(101101871) complement component 1, q subcomponent, C chain
  • Zebrafish(449803) complement component 1, q subcomponent, C chain
  • chicken(419503) complement component 1, q subcomponent, C chain
  • cow(509968) complement component 1, q subcomponent, C chain

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-C1QC antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-C1QC antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-C1QC antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-C1QC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Proteins

Product Number
Description
Species
Complement component C1q from human serum, ≥95% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human C1QC,
Species
human