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Merck

ADRA1B

adrenoceptor alpha 1B

Synonyms:
ADRA1, ALPHA1BAR
Species:
UniProtKB ID:
Gene ID:
  • Human(147) Summary: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008]
  • Mouse(11548) adrenergic receptor, alpha 1b
  • Rat(24173) adrenoceptor alpha 1B
  • domestic guinea pig(100735480) adrenoceptor alpha 1B
  • domestic cat(101092238) adrenoceptor alpha 1B
  • dog(403962) adrenoceptor alpha 1B
  • chicken(373890) adrenergic, alpha-1B-, receptor
  • Domestic Rabbit(100008731) adrenoceptor alpha 1B
  • sheep(101114869) adrenoceptor alpha 1B
  • cow(407140) adrenergic, alpha-1B-, receptor

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Small Molecule - Agonist

Product Number
Description
Species
Phenylephrine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Alfuzosin hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Alfuzosin hydrochloride, ≥98% (HPLC), solid,
Species
human
3-[(1R)-1-Hydroxy-2-(methylamino)ethyl]phenol, AldrichCPR,
Species
human
Methoxamine hydrochloride, ,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Naftopidil hydrochloride hydrate, solid,
Species
human
Terazosin hydrochloride, ≥98% (TLC), powder,
Species
human
Benoxathian hydrochloride, solid,
Species
human
Terazosin hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Terazosin Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ADRA1B (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, dog, hamster, horse, human, monkey, mouse, pig, rat
Application
ELISA
immunohistochemistry
Anti-ADRA1B (AB2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
Anti-ADRA1B antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
Anti-ADRA1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ADRA1B,
Species
human