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  • Glucose sensing via aggregation and the use of "knock-out" binding to improve selectivity.

Glucose sensing via aggregation and the use of "knock-out" binding to improve selectivity.

Journal of the American Chemical Society (2013-01-16)
Yan-Jun Huang, Wen-Juan Ouyang, Xin Wu, Zhao Li, John S Fossey, Tony D James, Yun-Bao Jiang
ABSTRACT

Aggregates of an amphiphilic monoboronic acid bearing a hydrophobic pyrene fluorophore were employed for highly modulating, sensitive, and selective ratiometric fluorescent sensing of glucose in aqueous solution. The selectivity for glucose was improved by "knock-out" binding of fructose by phenylboronic acid.

MATERIALS
Product Number
Brand
Product Description

Supelco
Pyrene, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
Sigma-Aldrich
Pyrene, puriss. p.a., for fluorescence, ≥99.0% (GC)
Pyrene, BCR®, certified reference material
Sigma-Aldrich
Pyrene, sublimed grade, 99%
Supelco
Pyrene, analytical standard
Sigma-Aldrich
Pyrene, 98%