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Key Documents

8.51015

Sigma-Aldrich

Dde-OH

Novabiochem®

Synonym(s):

Dde-OH, 2-Acetyldimedone

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About This Item

Empirical Formula (Hill Notation):
C10H14O3
CAS Number:
Molecular Weight:
182.22
UNSPSC Code:
12352115
NACRES:
NA.22

Quality Level

product line

Novabiochem®

Assay

≥98% (TLC)

form

powder

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

storage temp.

2-8°C

InChI

1S/C10H14O3/c1-6(11)9-7(12)4-10(2,3)5-8(9)13/h12H,4-5H2,1-3H3

InChI key

DIJDAMFZOHSRID-UHFFFAOYSA-N

General description

Reagent for the introduction of the Dde protecting group [1,2,3,4].

Associated Protocols and Technical Articles
Guide to Selection of Orthogonally -Protected Building Blocks for Fmoc SPPS

Literature references

[1] B. W. Bycroft, et al. (1993) J. Chem. Soc., Chem. Commun., 778.
[2] I. A. Nash, et al. (1996) Tetrahedron Lett., 37, 2625.
[3] F. Berst, et al. (2000) Tetrahedron Lett., 41, 6649.
[4] A. N. Acharaya, et al. (2001) J. Comb. Chem., 3, 612.

Linkage

Replaces: 01-63-0033

Analysis Note

Color (visual): white to slight yellow to yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (DC(012A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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