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860599C

Avanti

C18:1 Ceramide-1-Phosphate (d18:1/18:1(9Z))

Avanti Research - A Croda Brand 860599C

Synonym(s):

N-oleoyl-ceramide-1-phosphate (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C36H73N2O6P
CAS Number:
Molecular Weight:
660.95
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 1 mL (860599C-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860599C

concentration

1 mg/mL (860599C-1mg)

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCC/C=C\CCCCCCCC)=O)COP([O-])(O)=O.[NH4+]

General description

Ceramide-1-phosphate (C1P) is a ceramide-derived metabolite, which belongs to the class of bioactive lipid mediators.

Application

C18:1 Ceramide-1-Phosphate (d18:1/18:1(9Z)) may be used for fluorescence analysis of phosphatidic acid-binding tetravalent peptide (PAB-TP) phospholipid specificity. It may also be used in liposome cosedimentation assay to compare its affinity with α-synuclein-N.

Biochem/physiol Actions

Ceramide-1-phosphate (C1P) regulates cell survival, cell growth and death. It mediates inflammatory response and phagocytosis.

Packaging

5 mL Clear Glass Sealed Ampule (860599C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 3


Certificates of Analysis (COA)

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Characterization of alpha-synuclein N-terminal domain as a novel cellular phosphatidic acid sensor
Yamada H, et al.
The FEBS journal (2019)
Characterization of alpha-synuclein N-terminal domain as a novel cellular phosphatidic acid sensor
Yamada H, et al.
FEBS Journal (2019)
Development of a novel tetravalent synthetic peptide that binds to phosphatidic acid
Ogawa R, et al.
Testing, 10(7) (2015)
Blood sphingolipidomics in healthy humans: impact of sample collection methodology
Hammad SM, et al.
Journal of Lipid Research, 51(10), 3074-3087 (2010)
Development of a novel tetravalent synthetic peptide that binds to phosphatidic acid
Ogawa R, et al.
PLoS ONE, 10(7) (2015)

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