P38706
Phthalazine
98%
Synonym(s):
β-Phenodiazine, 2,3-Benzodiazine, 2,3-Diazanaphthalene, Benzo[d]pyridazine
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All Photos(3)
About This Item
Empirical Formula (Hill Notation):
C8H6N2
CAS Number:
Molecular Weight:
130.15
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
98%
form
crystals
bp
189 °C/29 mmHg (lit.)
mp
89-92 °C (lit.)
storage temp.
2-8°C
SMILES string
c1ccc2cnncc2c1
InChI
1S/C8H6N2/c1-2-4-8-6-10-9-5-7(8)3-1/h1-6H
InChI key
LFSXCDWNBUNEEM-UHFFFAOYSA-N
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 3 - Muta. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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A novel spleen tyrosine kinase (SYK) P-site inhibitor, 1,4-Bis (9-O dihydroquinidinyl) phthalazine/hydroquinidine 1,4-phathalazinediyl diether (C-61), (but not vehicle) markedly enhanced H(2)O(2)-induced apoptosis of primary leukemia cells from each of five relapsed B-lineage acute lymphoblastic leukemia (ALL) patients, as measured by
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A series of potent phthalazinone-based human H(1) and H(3) bivalent histamine receptor antagonists, suitable for intranasal administration for the potential treatment of allergic rhinitis, were identified. Blockade of H(3) receptors is thought to improve efficacy on nasal congestion, a symptom
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