N1415

Naratriptan hydrochloride

≥98% (HPLC)

• Synonym(s): Amerge, GR-85548A, N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide hydrochloride
• Empirical Formula (Hill Notation): C₁₇H₂₅N₃O₂S ·HCl
• CAS Number: 143388-64-1
• Molecular Weight: 371.93
• MDL number: MFCD08141821
• UNSPSC Code: 12352200
• PubChem Substance ID: 329818579
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• solubility: H₂O: ≥10 mg/mL
• originator: GlaxoSmithKline
• storage temp.: room temp
• SMILES string: Cl.CNS(=O)(=O)CCc1ccc2[nH]cc(C3CCN(C)CC3)c2c1
• InChI: 1S/C17H25N3O2S.ClH/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14;/h3-4,11-12,14,18-19H,5-10H2,1-2H3;1H
• InChI key: AWEZYKMQFAUBTD-UHFFFAOYSA-N
• Gene Information: human ... HTR1B(3351) , HTR1D(3352)

Description

Biochem/physiol Actions

Naratriptan hydrochloride is a triptan drug that is used to relieve acute migraine headaches. It has poor bioavailability, short half-life, and the incidence of migraine recurrence therefore, it is occasionally used.

Naratriptan hydrochloride is a serotonin 5-HT_1B/1D receptor agonist.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable