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255580

Sigma-Aldrich

Hydroxylamine hydrochloride

ACS reagent, 98.0%

Synonym(s):

Hydroxylammonium chloride

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About This Item

Linear Formula:
NH2OH · HCl
CAS Number:
Molecular Weight:
69.49
Beilstein:
3539763
EC Number:
MDL number:
UNSPSC Code:
12352300
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent

vapor pressure

0.001 hPa ( 50 °C)

Assay

98.0%

form

powder, crystals or chunks

reaction suitability

reaction type: C-H Activation
reagent type: catalyst

technique(s)

inhibition assay: suitable

impurities

≤0.005% S compounds
≤0.25 meq/g Titr. free acid

ign. residue

≤0.05%

pH

2.5-3.5 (20 °C, 50 g/L)

mp

155-157 °C (dec.) (lit.)

density

1.67 g/mL at 25 °C (lit.)

anion traces

sulfur compounds (as SO42-): ≤0.005%

cation traces

Fe: ≤5 ppm
NH4+:, passes test
heavy metals: ≤5 ppm (by ICP)

storage temp.

room temp

SMILES string

Cl.NO

InChI

1S/ClH.H3NO/c;1-2/h1H;2H,1H2

InChI key

WTDHULULXKLSOZ-UHFFFAOYSA-N

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Application

Powerful reducing agent. Converts aldehydes and ketones to oximes, and acid chlorides to hydroxamic acids. Used as catalyst, swelling agent, and copolymerization inhibitor.

Biochem/physiol Actions

MAO inhibitor; inhibits platelet aggregation.

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral

Target Organs

spleen

Storage Class Code

4.1A - Other explosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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William J Barnes et al.
Bio-protocol, 7(5), e2149-e2149 (2017-03-05)
Lignin is the second most abundant biopolymer on Earth, providing plants with mechanical support in secondary cell walls and defense against abiotic and biotic stresses. However, lignin also acts as a barrier to biomass saccharification for biofuel generation (Carroll and
Selective dissolution of manganese oxides from soils and sediments with acidified hydroxylamine hydrochloride.
Chao TT.
Soil Science Society of America Journal. Soil Science Society of America, 36(5), 764-768 (1972)
One-step Beckmann rearrangement from carbonyl compounds and hydroxylamine hydrochloride in Al2O3/CH3SO3H (AMA) as a new reagent.
Sharghi H and Sarvari MH.
J. Chem. Res. (M), 2001(10), 446-449 (2001)
Transamidation of primary amides with amines using hydroxylamine hydrochloride as an inorganic catalyst.
C Liana Allen et al.
Angewandte Chemie (International ed. in English), 51(6), 1383-1386 (2012-01-04)
Irina S R Rio et al.
Pharmaceutics, 13(11) (2021-11-28)
Liposome-like nanoarchitectures containing manganese ferrite nanoparticles covered or decorated with gold were developed for application in dual cancer therapy, combining chemotherapy and photothermia. The magnetic/plasmonic nanoparticles were characterized using XRD, UV/Visible absorption, HR-TEM, and SQUID, exhibiting superparamagnetic behavior at room

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